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This gradual approach helps to avoid the stark contrast that can sometimes result from more aggressive whitening treatments

Nutrients 7(10):88468858 Yesilada E, Honda G, Sezik E, Tabata M, Fusita T, Takenda Y (1995) Traditional medicine in Turkey, folk medicine in the inner Taurus mountain

(PubMed) Zempleni J, Trusty TA, Mock DM

However, pathological modifications oxidation, glycation, citrullination, carbonylation, and enzymatic carboxyethylation of cysteine (linked to ankylosing spondylitis) can render self-proteins immunogenic, driving autoimmune disease by presenting chemically altered peptides to the immune system as foreign antigens.

1 According to K.H