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Cleft lip and palate are considered to be polygenic and multifactorial in origin with involvement of many genetic and environmental factors

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Shukla, A., Perales, R

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10.1007/s40618-023-02258-2 259

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A pathognomonic sign is the appearance of a furrow, just lateral to the line of the philtral ridge, as the child puckers the lips

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Naturally occurring microorganisms are common in many foods and most are completely harmless (nature is full of microscopic life!)

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