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Description
Cleft lip and palate are considered to be polygenic and multifactorial in origin with involvement of many genetic and environmental factors

Shukla, A., Perales, R

10.1007/s40618-023-02258-2 259

A pathognomonic sign is the appearance of a furrow, just lateral to the line of the philtral ridge, as the child puckers the lips

Naturally occurring microorganisms are common in many foods and most are completely harmless (nature is full of microscopic life!)
