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These effects result in edema, demyelination, and peripheral nerve necrosis, impairing nerve conduction

Pharmacological enhancement of peripheral nerve regeneration in the rat by systemic acetyl-L carnitine treatment

doi: 10.1111/j.1440-1797.2007.00817.x

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ALC (200 mg/kg) reduced the rotational asymmetry induced by apomorphine and decreased the latency to initiate and total time in the narrow beam test, decreased MDA, increased catalase activity and GSH level, deterred reduction of nigral tyrosine hydroxylase (TH)-positive neurons and striatal TH-immunoreactivity, and decreased striatal GFAP