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Therefore, in the toxic damage caused by some poisons, the SIRT1-mediated PGC-1 pathway can play an important role by regulating the bodys antioxidant capacity and mitochondrial production and functional status
In the endoplasmic reticulum (ER) of eukaryotes, in contrast, GSH and GSSG are present in nearly equal concentrations (5)

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[DOI] [PubMed] [Google Scholar] Cortese S, Angriman M, Maffeis C, Isnard P, Konofal E, Lecendreux M, Mouren MC
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
