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doi: 10.1016/S0021-9150(00)00494-9

doi: 10.1016/j.foodchem.2016.09.163 199 YesiltasB.GregersenS.LgsgaardL.BrinchM

The FDA's December 2023 DCT guidance explicitly validates telemedicine visits as acceptable investigator-subject interactions for the majority of non-safety-critical protocol assessments, including symptom review, adverse event follow-up, protocol compliance discussions, and patient-reported outcome elicitation