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Studies have found that children with ASD often have lower Zn/Cu ratios than neurotypical children, which may indicate total body Zn deficiency or accumulation of Zn-antagonistic toxic metals [17, 141, 142]
Moreover, the abundance of bacteria carrying bile salt hydrolase and bile acid inducible enzyme in the gut microbiota of IBD patients, such as Firmicutes , Ruminococcaceae , Lachnospiraceae , and Eubacterium , is reduced

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