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These findings suggest that hepatic SREBP-2 significantly contributes to cholesterol synthesis, cholesterol uptake, and bile acid synthesis regulation, and that its inhibition by GLP-1RAs is essential for improving cholesterol metabolism in PA-treated HepG2 cells

The production of glutathione relies on SAMe, which is produced through the methylation pathway

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S., Jensen, P

To exclude potential confounding effects from variability in aggression intensity, we quantified the number of attacks initiated by CD1 aggressors across two confrontation sessions, specifically measuring attack frequency within the initial 50 s and the full 2-minute interaction period