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doi: 10.1056/NEJMoa071533

Reduced range of motion

An increase in ALT level indicated that administration of diquat led to acute hepatic necrosis in diquat-treated Fischer 334 rats

It is available only by prescription, and outside that approved indication it is prescribed off-label and often dispensed as a compounded preparation through 503A/503B compounding pharmacies for bodybuilding, fat-loss, or anti-aging purposes, uses the FDA has not evaluated or approved

Even with a well-structured diet and oral supplementation, certain nutrients may not reach adequate levels in patients with absorption limitations, increased physiological demand, or documented deficiency