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In particular, since H 2 S has very short half-life in biological fluids including cell culture medium and blood, how H 2 S reaches its presumed targets in the cells, and in the target tissues in the body when given in vivo, has been poorly understood
Given that cholesterol stabilizes high membrane curvature, cholesterol-mediated curvature of membranes may lead to altered lipid packing that engages A hydrophobic groups and promotes A fibrillar structures 64

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