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Neurologic abnormalities in cobalamin deficiency are associated with higher cobalamin "analogue" values than are hematologic abnormalities

The mechanisms underlying these effects are unknown and require additional research

Interestingly, ovarian-cancer-infiltrating Treg cells showing high OXPHOS dependency produce higher amounts of mitochondrial ROS and undergo apoptosis, thereby mediating the local production of immunosuppressive molecules able to act on other immune cell types and, consequently, a higher immune escape of tumors and failure of the clinical approach involving Treg depletion (48)

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5 Safety profile of antioxidant supplementation for treatment of erectile dysfunction