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10.1073/pnas.1402097111 13 DoyleJ

No Phase 3 results have been published as of May 2026

This disrupts axonal transport, destabilizes cytoskeletal architecture, and contributes to neuronal death (Duggal and Mehan, 2019)

Notably, silymarin use has not been linked to any reports of fatalities or major adverse effects
Phyther Res 28:14611467
