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It protects the body against UV radiation, mechanical damage, xenobiotics, and microorganisms, and it is highly susceptible to oxidative damage (149)

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While studies specifically examining the effects of myeloid HIF-1 deletion on macrophages in the context of bone regeneration are currently lacking, insights from other pathological conditions highlight its essential role in regulating macrophage survival and function

[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Abicic A., Adamec I., Habek M