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146 Moreover, the inhibition of PI3K-AKT phosphorylation, which enhances FOXO1 expression, can suppress DC maturation

Resistance mechanisms to these drugs have been identified that result in restoration of AR signalling through gain-of-function AR mutations, upregulation of constitutively active AR splice variants or increased intratumoural androgen biosynthesis
Marfanoid features in a child with combined methylmalonic aciduria and homocystinuria (CblC type)

2000;102:1886-1892 [Reference 122 in chapter] Fig

Zhao et al., 2022
