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By anchoring to these positively charged side chains, CLR01 disrupts the electrostatic and hydrophobic contacts necessary for oligomer and fibril formation
Romanyuk ND, Rigden DJ, Vatamaniuk OK, Lang A, Cahoon RE, Jez JM, et al
The day 3 sample showed a weak but specific IgG response that presumably pre-dated phage administration, but at both day 17 and week 16 post-phage initiation there was a robust IgG-mediated response, comparable to that reported in a prior patient 15
