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198 The APC gene was first identified as a mutated gene in familial adenomatous polyposis coli (FAP)

Another study has indicated that the C3-mediated protective effect on pancreatic islet cells involves AKT activation and c-Jun N-terminal kinase (JNK) inhibition upon treatment with pro-inflammatory cytokines, such as IL-1 and IFN- (178)

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But more human studies are needed to understand whether specific types and sources of prebiotics actually reduce occurrence of cancers or cell changes