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Gaining a deeper insight into what role ferroptosis play in cutaneous diseases could help provide and optimize therapeutic options

Beside, c-MYC and other transcription factors, such as mTOR and HIF-1, can act synergistically to improve glycolysis and promote cancer proliferation (182, 183)

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Thus, a higher Bcl-2/Bax ratio is posted as a predominance of Bcl-2, which may inhibit apoptosis and apparently promotes cell survival

Figure 11: The Poisson distribution model was first published in 1837 by Simon Denis Poisson (left), a French mathematician and physicist, to analyse the probability of juries reaching the right verdict