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This M1 polarization leads to increased expression of pro-inflammatory markers (such as CD80 and CD86) and cytokines (like IL-1, IL-6, and IL-12), while reducing levels of immunosuppressive cytokines such as IL-10

By modulating this immunometabolic axis, GLP-1RAs may indirectly attenuate thyroid autoimmunity, supporting their potential role as dual-purpose agents in patients with coexisting metabolic and AITD

J Neurochem 135(3):616629 Ma L, Niu W, Yang S, Tian J, Luan H, Cao M, Xi W, Tu W et al (2018) Inhibition of mitochondrial permeability transition pore opening contributes to cannabinoid type 1 receptor agonist ACEA-induced neuroprotection

Si se altera el equilibrio entre ellos, puede afectar negativamente la resolucin de pico, la retencin de analito y el rendimiento general del mtodo

Niculescu-Duvaz, D., Negoita-Giras, G., Niculescu-Duvaz, I., Hedley, D