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2-Mercaptonicotinoyl glycine, a new potent melanogenesis inhibitor, exhibits a unique mode of action while preserving melanocyte integrity

In the HCC ACLY KO cells, we quantified acetyl-CoA in the presence or absence of acetate, finding that acetyl-CoA abundance is elevated in ACLY KO cells in the presence of acetate and decreases back to that in WT cells in its absence (Figure 1F)

the combination is not clinically validated

Cutis 2019;103:E16E17

These methodologies have also been used to elucidate microbial activities, behaviors, strategies, and processes during infections (52)
