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Future directions should focus on optimizing pharmacokinetics and safety profiles, with strategies such as nanotechnology-based delivery systems and prodrugs offering promising solutions [142, 143]

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J Biol Chem 285(39):3027430281 [DOI] [PMC free article] [PubMed] [Google Scholar] Olson KR, Straub KD (2016) The role of hydrogen sulfide in evolution and the evolution of hydrogen sulfide in metabolism and signaling

KraemerWJNindlBCMarxJOGotshalkLABushJAWelschJRet al

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