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To sum up, there are several generations of anti-EpCAM antibodies with different effector mechanisms, including ADCC, CDC, T-cell engaging, providing activatory cytokines for immune cells, and delivering toxins to the tumor cells
These approaches can be deployed to overcome drawbacks such as protecting the peptide from proteolytic degradation and facilitation of cell uptake
Planta 197:4225 Dabrowska G, Katai A, Goc A, Szechynska-Hebda M, Skrzypek E (2007) Characteristics of the plant ascorbate peroxidase family
