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Rosenfeld, MD Genetic causes of growth failure can be broadly divided into 5 categories: chromosomal defects such as Down syndrome and Turner syndrome, inborn metabolic defects, osteochondrodysplasias, genetic defects of the thyroid axis that result in neonatal or childhood hypothyroidism, and genetic defects of the growth hormone (GH)/ insulin-like growth factor-I (IGF-I) axis

[43] Embryotoxic and teratogenic effects (syndactylia and oligodactylia) have been demonstrated in animals receiving oral ketoconazole doses at 10-times the maximum recommended human dose

Agents encompassed by the present invention can be tethered to amine functionalized gold nanoparticles (see, e.g., Lippard et al (2009) JACS 131: 14652-14653)

Your brain has not yet adapted to the altered neurotransmitter balance

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