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Moreover, the potential of personalized medicine in managing oxidative stress-related neurodegeneration is gaining momentum: genetic variants in the Nrf2 signaling pathway or SIRT1-mediated deacetylation affecting astrocytic GSH synthesis (e.g., regulating glutamate cysteine ligase catalytic subunit expression), combined with biomarkers like individual GSH levels and Nrf2 activity, could enable tailored interventions
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Rico-Garca D, Ruiz-Rubio L, Prez-Alvarez L, Hernndez-Olmos SL, Guerrero-Ramrez GL, Vilas-Vilela JL (2020) Lignin-based hydrogels: Synthesis and applications
Ballard TM, Knoflach F, Prinssen E, Borroni E, Vivian JA, Basile J, et al
