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The boxplot results show that the infiltration of CD8(+) T cells is significantly reduced in the influenza group, and the other T cell subpopulations also show a trend of reduced infiltration [Fig

Cell 127 , 397408 (2006)

Authors concluded that, in the process of prostate carcinogenesis, activating histone modifications on GSTP1 are lost and subsequently DNA becomes methylated and inaccessible resulting in transcriptional silencing thus demonstrating interplay between histone reprogramming and promoter region methylation (Okino et al., 2007)