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Antidepressants Tricyclic antidepressants and selective serotonin reuptake inhibitors used for depression can also cause sexual dysfunction, such as lowered desire or arousal, delayed orgasm, and anejaculation

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This same idea applies to weight loss

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This explanation may appear fanciful but recent data suggest that AMPARs are in fact metastable within the plasma membrane and can quickly transition to monomers and dimers, only to readily form tetramers again [57]