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These different scales can be used in combination to identify abnormalities or severity of different symptoms which may present in FRDA, and have been used in the clinical trials which tested the compounds discussed in this review paper

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The frequent showers dash from the passing clouds, The hills are peeping through their wintery shrouds." Durfee's "What Cheer?" EAR after year the free dwellers upon Rhode Island had beheld a scene like that described by the poet, and more cruel wintery storms, piling their huge snow-drifts, had howled around their dwellings, but never in their history had the March winds and April floods appeared to them so cheerless and mournful as in the spring of 1777

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