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Meanwhile, in PD, a pathological Syn aggregation can induce microglial activation and dysfunction [17]

multiple doses), and diet [15]

Since mitochondria are essential to our very existence, it is unsurprising that the effects of mitochondrial diseases can be severe, and sometimes lethal, spanning a wide-ranging spectrum of physiological and biochemical symptoms [1,3,4] (see Table 1 for examples)

High-performance liquid chromatography (HPLC) analysis revealed that GA was metabolized into several structurally similar compounds, including pyrogallol, 2- O -methyl-phenylenetriol, and 4-O-methylgallic acid (Yasuda et al., 2000)

2.1.3 Metabolomics Biomarkers allow disease detection, assessment, and cardiovascular risk management