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Trends Pharmacol Sci 20:424429 Miller JS, Barr JL, Harper LJ et al (2014) The GSK3 signaling pathway is activated by cocaine and is critical for cocaine conditioned reward in mice

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As the only FDA-approved treatment for IS, recombinant tissue plasminogen activator (rtPA) has been widely validated for its efficacy since it received clinical application approval in 1996

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