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Cell Mol Gastroenterol Hepatol 12: 16171641, 2021

Proteolysis-targeting chimera (PROTAC): Current applications and future directions

Dihexa is an oligopeptide, which means it is composed of a short chain of amino acids
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Further, RA patients with serious infections before the initiation of TNF- inhibitor therapy were not at increased risk of subsequent serious infection and the hospitalization rate was comparable between patients continuously treated with the same TNF- inhibitor and patients who switched to another TNF- inhibitor, or even to a different mode of action [54]
