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Laser treatments are best to reduce dark spots and are not typically recommended for whitening the entire face or part of body by most of the doctors in the world.

Recently, all-trans retinoic acid (ATRA), was shown to induce the expression of GS selectively (no effect on GCLC or GCLM) and GSH levels in myeloid-derived suppressor cells [141]

Injectable anti-ageing protocol: 12 mg daily or 5 days on / 2 off , cycle 30 days on / 14 days off , minimum 23 cycles for substantial change Topical anti-ageing protocol: 2 %3 % serum, twice daily, minimum 12 weeks continuous use, paired with daily SPF 50 sunscreen Combination protocol: low-dose injectable ( 1 mg 3/week) + topical 2 % serum daily - typically the most powerful approach for patients 40+ See our related pieces on anti-ageing treatments in Mumbai and how to look younger without looking fake

Toxics , 3(1), 20-62

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