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These changes lead to central sensitization, where non-painful stimuli are perceived as painful (allodynia), and pain responses are amplified (hyperalgesia)
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Jul 16 2021;10(14)doi:10.3390/jcm10143151
Ann Transl Med 6:467 Higgins T, Chaykin S, Hammond KB, Humbert JR (1972) Trimethylamine N-oxide synthesis: a human variant
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