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NAC rapidly increases extracellular glutamate via activation of system xc - , which helps normalize these neurochemical disruptions [44]

DJ-1 is another gene reported to cause a familial early onset PD (Puschmann, 2013)

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These results were consistent with previous studies suggesting that glucose is a main source of NADPH production and increasing glucose concentration can acutely promote NADPH generation from NADP + and increase intracellular NADPH levels (51, 52)
