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However, the single measure of cobalamin level alone may not be reliable for detecting B12 deficiency

In turn, IGF-1 binds to a membrane-spanning homodimeric receptor (IGF-1R), which determines the autophosphorylation of the intracellular -subunit of IGF-1R and the stimulation of intracellular signaling pathways (16)

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Cell pellets were resupended in ice-cold buffer 1 containing 20 mM imidazole, 50 mM Na x H y PO 4 , 300 mM NaCl, pH 8.0 at 4 C and stirred on ice with DNase I and 10 mg/mL lysozyme for 1 h before sonication

Fundamental and Applied Toxicology