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Findings from pre-clinical study found that both proBDNF and mature BDNF were expressed abundantly in the rat brainstem, hippocampus, and cerebellum between embryonic day 20 and postnatal day 8

MTT assay The viability rate of cells on the PU-CA scaffold was measured using MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide

Collectively the prior work support moving forward with a Phase II, placebo-controlled study of D+Q (NCT04685590)

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Sensitivity is less then 50 nM for both Free and Total GSH