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A previous study on a different strain, Bifidobacterium breve CCFM1025, also demonstrated improvements in both gastrointestinal and psychological symptoms in patients with major depressive disorder (MDD) (Tian et al., 2022)

Firstly, one of the primary obstacles is the absence of reliable biomarkers in PF patients that can accurately indicate the extent of lipid peroxidation and ferroptosis, making it difficult to assess disease severity and progression

NSPs, particularly NE, are closely related to multiple key pathological features of COPD, including inflammatory responses, excessive mucus secretion, and emphysema formation

Nano-medicine assembly-based structure advancement for COVID-19 vaccination Assembly-based structure is used for fabrication of CoV-2 nanovaccines (NVs), via encapsulation of CoV antigens or exposing them on a NP surface, with an advantage of less aggregation and an improved vaccine efficacy , via (i) protection of COVID-19 antigens from degradation, during the quest of vaccination, (ii) controlling the amount of antigens to be delivered within the NV from the NP-matrix, and (iii) regulation of antigen uptake and processing [118]

ZIL is not cell permeable, less toxic to cells and tissues, and has great potential as a vehicle for various hydrophobic drugs