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In HUA and its ensuing complications, MSU crystals also escalate their role in prompting macrophages to produce inflammatory factors by mediating other cytokines such as leptin (45)
[DOI] [PubMed] [Google Scholar] de Keizer PL
The increased ROS production induced by Ang II leads to vasoconstriction and promotes inflammation, contributing to the development and maintenance of hypertension [81]
Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione
