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The mitochondria-targeted anti-oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance

4K and S9A)

These investigations have examined the compound's biochemical effects in cultured cells and animal models as part of broader research into NNMT and cellular metabolism Importantly, these findings relate to preclinical research and should not be interpreted as evidence of established clinical efficacy, safety or therapeutic benefit in humans

FM: Conceptualization, Funding acquisition, Supervision, Writing original draft, Writing review & editing

(2006) The role of glutathione in disulphide bond formation and endoplasmic-reticulum-generated oxidative stress