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Huang, C., Snider, F

While the finding that copper potently blocks 1 3 2 GABA A Rs suggests that this metal inhibits fast synaptic, or phasic GABAergic signalling in contrast to zinc, which can only inhibit tonic GABAergic signalling, it is important to note extrasynaptic receptors are sensitive to copper block and, therefore, tonic GABAergic signalling as well

Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: A mechanistic insight