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doi: 10.1111/jhn.12697
Predictably, melatonin synthesis increases as light decreases and reaches its maximal level between 2:00 and 4:00 a.m

Injections are the primary treatment

Renaudin, F
Neutrophil activation and clonal CAR-T re-expansion underpinning cytokine release syndrome during ciltacabtagene autoleucel therapy in multiple myeloma