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Before treatment her skin had creases and slackness
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Reviews describe regenerative and protective actions, roles in skin regeneration, and modulation of multiple cellular pathways but this is largely mechanistic and preclinical work, not large human efficacy trials

doi:10.1016/S0040-4020(99)00386-5

In addition, newly developed metforminloaded hyaluronic acidderived carbon dots inhibit GLS1 and downregulate GLUT1