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The primary outcomes assessed included the one-repetition maximum (1RM) strength, indicators of muscle hypertrophy (as measured by DXA, CT, and biopsy), and rates of MPS (utilizing deuterated water as a tracer)

This pathway includes both forward and reverse

Another important factor is diet

Additionally, gut microbiota can also modulate the production of other pro-inflammatory molecules, such as TNF-, IL-1, and IL-6, which can contribute to the development of atherosclerosis (120, 121)

Insulin resistance may be a critical metabolic link between migraine and its comorbidities (23), as insulin regulates mitochondrial signaling pathways (24)