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HUBERMAN: So you can get really robust increases in growth hormone, but because there are ghrelin increases as well, you get big increases in hunger and anxiety in some people and lesser in others

In mice, BPC-157 attenuated withdrawal seizures over 24 hours following abrupt alcohol cessation (Boban Blagaic et al., 2004)

MECHANISM CATEGORIES RESEARCH CONDITIONS SAFETY Side effects Limited human safety data Animal studies report wide therapeutic window Known interactions Methyl-donor depletion theoretical with chronic dosing (NNMT methylates nicotinamide using SAM) Contraindications Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Not FDA-approved