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The similar effects of glo-1(-) , glo-3(-) , and ccz-1(-) mutants on gut granule protein localization (Fig 2) [19], the cytoplasmic mislocalization of GLO-1 in glo-3(-) and ccz-1(-) mutants (Fig 8), the ability of the fast exchange GLO-1(D132A) mutants to restore gut granules in glo-3(-) and ccz-1(-) mutants (Figs 6 and 7 and Tables 1 & 2), and the ability of GLO-3 to directly bind CCZ-1 (Fig 1), strongly support the model that CCZ-1, by functioning with GLO-3, can regulate GLO-1