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(3) Iron homeostasis modulation: iron chelation with deferoxamine (DFO) and inhibition of NCOA4dependent ferritinophagy are illustrated as means to lower the labile iron pool and reduce ironcatalyzed lipid peroxidation

Death is usually due to cerebral edema, which causes an increase in intracranial pressure, and a reduced level of vigilance
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Jones TT, Brewer GJ

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