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In addition, combination of NNMTi with exercise further increases systemic energy expenditure, accelerates fat breakdown, and enhances muscle strength and endurance

This method can be particularly beneficial for individuals with absorption issues or those who may not be getting enough B12 through diet alone

Teach stress management techniques and coping strategies to the patient

However, its relationship with other cognitive and cardiovascular complications remains controversial

Moreover, in a dose-dependent manner, both borderline and low levels of vitamin B 12 occurred to be associated with the presence of distinct neuropathies and macrocytic anemia [41]
