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Inhibitors Pieces of evidence for the transcriptional regulation of NRF2 highlighted that modifications of the NFE2L2 promoter region such as hypermethylation or single nucleotide polymorphisms, are responsible for a decreased NRF2 expression

To determine the in vivo functional contribution of ACTL6A to tumor progress, we performed GC xenograft mouse model experiments

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However, the heterogeneity in study designs, populations, and covariates underscores the need for larger, longitudinal, and mechanistically focused investigations to fully elucidate the epigenetic consequences of NSW exposure and deriving health issues