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Researchers believe this is due to increased ROS (increased oxidative stress) in the pancreatic beta cells.[ref] Related article : Type 2 Diabetes Genes Fatty liver disease: High homocysteine levels are associated with NAFLD (fatty liver disease, MAFLD)

Furthermore, the myristoylated N-terminus, distinct amino acid residues, and intrinsically disordered, low-complexity regions of FSP1 were identified as essential for FSP1-dependent phase separation [49]

Caffeine is metabolized by the liver, similar to alcohol, which can lead to increased oxidative stress

& Ashraf, M
doi: 10.1038/s41576-022-00470-z
