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Description
This longevity of research interest is itself informative: compounds that fail to replicate across independent laboratories typically disappear from the literature within a decade
So if you are 100 lbs overweight you should lose between 70-80 lbs, for a 200 lbs overweight patient, the estimated weight loss is 140-160 lbs

Do you have a B12 deficiency

The practical result studied in trials is lower appetite and a small bump in resting energy use

Also known as copper peptide-1 or copper tripeptide-1
