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Understanding Melasma: Pathophysiology and Treatment Challenge Melasma is defined as an acquired hyper-pigmentation disorder characterised by symmetrical brown-to-grey macules on sun-exposed facial areas

The internal standards were used both to assure injection and chromatographic consistency

[Google Scholar] 29.Hondal RJ, Marino SM, Gladyshev VN

White CC, Viernes H, Krejsa CM, Botta D, Kavanagh TJ

7 Excess iron stimulates the formation of reactive oxygen species (ROS) via the Fenton reaction, oxidizing phospholipids in unsaturated fatty acid acyl tails, thereby initiating lipid peroxidation
