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Pigmentation can be significantly reduced, but long-term maintenance depends on sun protection, lifestyle habits, and follow-up treatments

Several experimental therapies for CIPN prevention have reached the clinical stage of testing

Crone JS, Lutkenhoff ES, Vespa PM, Monti MM

In addition, we also assessed the intracellular levels of reduced GSH and observed a significant reduction in these levels in HK-2 cells H 2 O 2 stimulation compared with those in normal cells (Figure 3G)

These therapies are still experimental and not yet ready for clinical practice, but they illustrate the importance of the concept of continuous dopaminergic stimulation in therapeutic research for PD