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are $70-100 billion [4,5] and in excess of $600 billion worldwide [6]

J Food Sci Technol 58:111 [DOI] [PMC free article] [PubMed] [Google Scholar] Adisakwattana S (2017) Cinnamic acid and its derivatives: mechanisms for prevention and management of diabetes and its complications

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Overexpression of these growth factors is associated with glaucoma, as it disrupts ECM turnover, leading to excessive ECM accumulation in the AH outflow pathway, increasing outflow resistence and ultimately resulting in elevated IOP, which contributes to glaucoma development (83, 84)